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Published byJohannes Sipilä Modified over 5 years ago
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Figure 1 Imaging assessments of luminal stenosis, haemodynamic
obstruction, and myocardial ischaemia in different patients Figure 1 | Imaging assessments of luminal stenosis, haemodynamic obstruction, and myocardial ischaemia in different patients. a | Invasive coronary angiogram demonstrating intermediate stenosis (arrow) in the proximal left anterior descending coronary artery. b | Coronary CT angiogram in the same patient demonstrating >50% stenosis in the proximal left anterior descending coronary artery (arrow). c | Fractional flow reserve–CT image, again in the same patient, highlighting that this lesion is functionally significant (FFRCT = 0.74). PET perfusion measurements of absolute myocardial blood flow during d | rest and e | stress, resulting in impaired myocardial flow reserve in the inferior wall during stress (arrow). f | Stress cardiovascular magnetic resonance perfusion study with perfusion defect in the inferior wall (arrows). g | Fused coronary CT angiography and single-photon emission computed tomography (SPECT) images demonstrating stenosis in the intermediate and diagonal vessels (white arrows), with a corresponding myocardial perfusion defect in the anterolateral wall (blue arrow). Note that panels a–c are derived from the same patient; the images in panels d–g are each from different patients. Permission obtained for panels a–c from Charles Taylor (HeartFlow Inc., Redwood, California, USA) and for panel g from Michelle Williams (Centre for Cardiovascular Science, University of Edinburgh, UK). Permission obtained for panels a–c from Charles Taylor (HeartFlow Inc., Redwood, California, USA) and for panel g from Michelle Williams (Centre for Cardiovascular Science, University of Edinburgh, UK) Dweck, M. R. et al. (2016) Imaging of coronary atherosclerosis — evolution towards new treatment strategies Nat. Rev. Cardiol. doi: /nrcardio
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