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T-cell activation and induction of apoptosis in epithelial cells of oral lesions induced by 4-NQO.
T-cell activation and induction of apoptosis in epithelial cells of oral lesions induced by 4-NQO. A, IHC images for IFNγ, pSTAT1, and granzyme B in low-grade oral lesions, and the corresponding quantification in low-grade and high-grade lesions from control and anti–PD-1 groups. B, Double staining for TUNEL and K14 and quantification of apoptosis in oral lesions from control and anti–PD-1 groups. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****P < Jin Wang et al. Cancer Prev Res 2017;10: ©2017 by American Association for Cancer Research
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