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The bioavailability of morphine applied topically to cutaneous ulcers

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Presentation on theme: "The bioavailability of morphine applied topically to cutaneous ulcers"— Presentation transcript:

1 The bioavailability of morphine applied topically to cutaneous ulcers
Maria D.C. Ribeiro, MRCP, Simon P. Joel, PhD, Giovambattista Zeppetella, MRCGP  Journal of Pain and Symptom Management  Volume 27, Issue 5, Pages (May 2004) DOI: /j.jpainsymman

2 Fig. 1 Plasma morphine, M6G, and M3G concentration in 6 patients after 10 mg subcutaneous morphine infused over 4 hours (mean ± SD). Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )

3 Fig. 2 Plasma morphine and M6G concentrations in patient 6 after 10 mg topical morphine in Intrasite gel. Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )

4 Fig. 3 Percentage dose absorbed against time for patient 6 after 10 mg topical morphine in Intrasite gel. Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )


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