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CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression The transmembrane and cytoplasmic regions.

Published byTyyne Järvenpää Modified over 5 years ago

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Presentation on theme: "CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression The transmembrane and cytoplasmic regions."— Presentation transcript:

1 CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression The transmembrane and cytoplasmic regions of CD147 are sufficient to mediate the interaction with MCT1. The CD2–CD147 hybrid protein was immunoprecipitated from transfected RBL cells using anti‐CD2 antibody, and western blotted for MCT1 (lane 1) and MCT2 (lane 2). MCT1 is clearly detected, contrasting with Figure 2, in which MCT1 is not detected in CD2 immunoprecipitate from CD2‐transfected RBL cells. The bars represent 50 μm. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER. EMBO J, Volume: 19, Issue: 15, Pages: , First published: 01 August 2000, DOI: ( /emboj/ )

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