1. Aliskiren, the orally effective renin inhibitor, provides antihypertensive efficacy at least equivalent to the ARB irbesartan in patients with hypertension.
Aliskiren, the orally effective renin inhibitor, provides antihypertensive efficacy at least equivalent to the ARB irbesartan in patients with hypertension. Bars indicate placebo-corrected reductions from baseline in mean sitting diastolic BP (DBP) after once-daily treatment for 8 wk with either aliskiren (▪) or irbesartan (▒). *P < 0.05 versus irbesartan 150 mg. Reproduced from reference (43) with permission.
Dominik N. Müller, and Friedrich C. Luft CJASN 2006;1:
©2006 by American Society of Nephrology