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The ReSTAGE Collaboration: defining optimal bleeding criteria for onset of early menopausal transition  Siobán D. Harlow, Ph.D., Ellen S. Mitchell, Ph.D.,

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Presentation on theme: "The ReSTAGE Collaboration: defining optimal bleeding criteria for onset of early menopausal transition  Siobán D. Harlow, Ph.D., Ellen S. Mitchell, Ph.D.,"— Presentation transcript:

1 The ReSTAGE Collaboration: defining optimal bleeding criteria for onset of early menopausal transition  Siobán D. Harlow, Ph.D., Ellen S. Mitchell, Ph.D., Sybil Crawford, Ph.D., Bin Nan, Ph.D., Roderick Little, Ph.D., John Taffe, Ph.D.  Fertility and Sterility  Volume 89, Issue 1, Pages (January 2008) DOI: /j.fertnstert Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Distribution of Kaplan Meier estimates of age at markers of the Early (a is persistent >6-day difference, b is SD >6 day, c is ≥45 day, d is SD >8 day, e is irregular) and late (f is ≥60-day segment) menopausal transition by cohort study (bold line represents 50th percentile, box represents 25th and 75th percentile, dashed line represents 10th and 90th percentiles). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Estimated unadjusted associations between bleeding markers and FSH longitudinal data in SWAN and MWMHP. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions


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