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Hisato Takagi, MD, PhD, Masafumi Matsui, MD, Takuya Umemoto, MD, PhD 

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Presentation on theme: "Hisato Takagi, MD, PhD, Masafumi Matsui, MD, Takuya Umemoto, MD, PhD "— Presentation transcript:

1 Off-Pump Coronary Artery Bypass May Increase Late Mortality: A Meta-Analysis of Randomized Trials 
Hisato Takagi, MD, PhD, Masafumi Matsui, MD, Takuya Umemoto, MD, PhD  The Annals of Thoracic Surgery  Volume 89, Issue 6, Pages (June 2010) DOI: /j.athoracsur Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Quality of reporting of meta-analyses [9] flow diagram for the meta-analysis. (CABG = coronary artery bypass grafting.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Forest plot (graphic display of findings of systematic reviews and meta-analyses) of late all-cause mortality among patients randomized to off-pump versus on-pump coronary artery bypass grafting. Gray boxes represent risk ratio. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Leave-one-out meta-analysis excluding individual results one at a time and recalculating the pooled risk ratio (gray boxes) estimates for the remaining results. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Meta-regression for duration of follow-up on the logarithm of point estimate (risk ratio). Each result is represented by a circle proportional to its weight in the analysis. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Funnel plot of the logarithm of point estimate (risk ratio) versus the inverse standard error for each result (circles). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

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