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Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy  Damien Leger, MD, Moshe Laudon,

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Presentation on theme: "Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy  Damien Leger, MD, Moshe Laudon,"— Presentation transcript:

1 Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy  Damien Leger, MD, Moshe Laudon, PhD, Nava Zisapel, PhD  The American Journal of Medicine  Volume 116, Issue 2, Pages (January 2004) DOI: /j.amjmed

2 Figure Frequency distribution of nocturnal 6-sulfatoxymelatonin excretion in healthy volunteers (n = 30 [open squares], ages 20 to 35 years; n = 29 [open circles], ages ≥55 years) and in patients with insomnia aged ≥55 years (n = 517 [closed circles]). The American Journal of Medicine  , 91-95DOI: ( /j.amjmed )


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