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A, P causes G2-M arrest with apoptosis in asynchronous population of PC-3 when exposed to 1.5 and 5 μmol/L P for various time points. A, P causes G2-M arrest with apoptosis in asynchronous population of PC-3 when exposed to 1.5 and 5 μmol/L P for various time points. The DNA histograms were generated by flow cytometry and the percentage of cells in each phase of the cell cycle was determined using ModFit analysis. B, P causes significant apoptosis in asynchronous population of HL-60 cells from 6 h onwards when treated with concentrations of 1.5 and 5 μmol/L P for various time points. Kalpana S. Joshi et al. Mol Cancer Ther 2007;6: ©2007 by American Association for Cancer Research
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