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Figure Summary of potential treatment approaches for HAND

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1 Figure Summary of potential treatment approaches for HAND
Summary of potential treatment approaches for HAND Shown are different treatment approaches for HAND targeting key pathogenic processes, involving blocking of lymphocyte trafficking into the CNS (A), reduction of monocyte trafficking (B), modification of NFkß with reduced viral replication (C), and reduction of microglial activation (D). Images were modified from Servier Medical Art, licensed under a creative common license. DMF = Dimethyl fumarate; HAND = HIV-associated neurocognitive disorders; NFkß = nuclear factor ĸß Björn Ambrosius et al. Neurol Neuroimmunol Neuroinflamm 2019;6:e551 Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.


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