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Ye-Guang Chen, Zhongwei Li, Xiao-Fan Wang  Cell Stem Cell 

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Presentation on theme: "Ye-Guang Chen, Zhongwei Li, Xiao-Fan Wang  Cell Stem Cell "— Presentation transcript:

1 Where PI3K/Akt Meets Smads: The Crosstalk Determines Human Embryonic Stem Cell Fate 
Ye-Guang Chen, Zhongwei Li, Xiao-Fan Wang  Cell Stem Cell  Volume 10, Issue 3, Pages (March 2012) DOI: /j.stem Copyright © 2012 Elsevier Inc. Terms and Conditions

2 Figure 1 Heregulin and IGF-1 via PI3K/Akt and Activin via Smad2/3 Cooperate to Maintain Self-Renewal of hESCs Red indicates the activated state of signaling molecules, whereas blue indicates the repressive state. The dashed line indicates the regulation with unclear mechanisms. Cell Stem Cell  , DOI: ( /j.stem ) Copyright © 2012 Elsevier Inc. Terms and Conditions

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