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Acute phosphate nephropathy

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Presentation on theme: "Acute phosphate nephropathy"— Presentation transcript:

1 Acute phosphate nephropathy
Alexander K. Rocuts, Sushrut S. Waikar, Mariam P. Alexander, Helmut G. Rennke, Ajay K. Singh  Kidney International  Volume 75, Issue 9, Pages (May 2009) DOI: /ki Copyright © 2009 International Society of Nephrology Terms and Conditions

2 Figure 1 Renal biopsy findings in acute phospho-nephropathy. (a) Coarse basophilic, rounded deposits of calcium phosphate are present within the lumina of tubules (hematoxylin–eosin, high-power field, original magnification × 40). (b) The widespread multifocal nature of the intratubular calcium–phosphate deposits is best illustrated with the von Kossa stain (von Kossa stain, high-power field, original magnification × 60). (c) Glomeruli displaying mesangial sclerosis with the formation of distinctive acellular nodules (periodic acid-Schiff stain, high-power field, original magnification × 40). Kidney International  , DOI: ( /ki ) Copyright © 2009 International Society of Nephrology Terms and Conditions

3 Figure 2 Acute phosphate nephropathy progression after OSPS exposure. Graph shows the trends of estimated glomerular filtration rate, serum calcium and phosphate, and total urine protein-to-creatinine ratio at baseline and up to 5 months after exposure to OSPS. The arrow marks the time when the patient was exposed to OSPS. Kidney International  , DOI: ( /ki ) Copyright © 2009 International Society of Nephrology Terms and Conditions

4 Figure 3 Fleet Phospho-soda warning in the hospital clinical information system. Kidney International  , DOI: ( /ki ) Copyright © 2009 International Society of Nephrology Terms and Conditions


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