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Intrafollicular antimüllerian hormone levels predict follicle responsiveness to follicle- stimulating hormone (FSH) in normoandrogenic ovulatory women.

Published byGabriela Paluch Modified over 5 years ago

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Presentation on theme: "Intrafollicular antimüllerian hormone levels predict follicle responsiveness to follicle- stimulating hormone (FSH) in normoandrogenic ovulatory women."— Presentation transcript:

1 Intrafollicular antimüllerian hormone levels predict follicle responsiveness to follicle- stimulating hormone (FSH) in normoandrogenic ovulatory women undergoing gonadotropin releasing-hormone analog/recombinant human FSH therapy for in vitro fertilization and embryo transfer  Daniel A. Dumesic, M.D., Timothy G. Lesnick, M.S., Jacques P. Stassart, M.D., G. David Ball, Ph.D., Ashley Wong, M.S., David H. Abbott, Ph.D.  Fertility and Sterility  Volume 92, Issue 1, Pages (July 2009) DOI: /j.fertnstert Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Correlations between antimüllerian hormone (AMH) and hormone concentrations in follicles of 26 normoandrogenic ovulatory women undergoing in vitro fertilization/embryo transfer. The AMH levels statistically significantly correlated with estradiol (E2) (R = +0.26; P<.025) and follicle-stimulating hormone (FSH) (R= −0.74; P<.0001) concentrations as well as the ratios of E2/FSH (R = +0.70; P<.000), E2/androstenedione (R = +0.26; P<.025) and E2/testosterone (R = +0.31; P<.0005). Conversion to SI units: AMH ∗ 7.14 pmol/L. The first follicle of each ovary was selected by size (at least 16 mm in diameter) and accessibility to replicate the follicle size at which AMH previously has been shown to predict enhanced oocyte development. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

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