1. Normal diurnal variation in serum cortisol concentration in asthmatic children treated with inhaled budesonide 
Benjamin Volovitz, MD, Arieh Kauschansky, MD, Moshe Nussinovitch, MD, Liora Harel, MD, Itzhak Varsano, MD 
Journal of Allergy and Clinical Immunology 
Volume 96, Issue 6, Pages (December 1995)
DOI: /S (95)
Copyright © 1995 Mosby, Inc. Terms and Conditions

2. FIG. 1
Circadian rhythm of serum cortisol secretion. The serum cortisol concentrations of all the children, measured every 30 minutes during 24 hours, showed a normal pattern, including high concentrations in the early morning, several concentration peaks during the day, and no evidence of nocturnal suppression.
Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) )
Copyright © 1995 Mosby, Inc. Terms and Conditions

3. FIG. 2
Mean 24-hour serum cortisol concentration. The mean 24-hour serum cortisol time concentration profile was normal, including highest concentrations in the early morning, several concentration peaks during the day, with a decrease during the night and an increase toward the morning. The pattern in our group of children (bold line) was similar to that observed in healthy adults and children (fine lines).7, 9-12
Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) )
Copyright © 1995 Mosby, Inc. Terms and Conditions

4. FIG. 3
Corticotropin stimulation test. The mean morning cortisol concentration ranged from 8.5 to 18 μg/dl (234 to 497 nmol/L), much above the 8:00 AM low normal limit of 4 μg/dl (110 nmol/L) in our laboratory. The mean serum concentration at 60 minutes after the 0.25 μg/dl intravenous corticotropin stimulation test ranged from 22.7 to 41.6 μg/dl (627 to 1148 nmol/L), much above the low normal limit of 18 μg/dl (497 nmol/L) in our laboratory.
Journal of Allergy and Clinical Immunology  , DOI: ( /S (95) )
Copyright © 1995 Mosby, Inc. Terms and Conditions