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Jenner's Irony: Cowpox Taps into T Cell Evasion

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Presentation on theme: "Jenner's Irony: Cowpox Taps into T Cell Evasion"— Presentation transcript:

1 Jenner's Irony: Cowpox Taps into T Cell Evasion
Gavin W.G. Wilkinson, Paul J. Lehner  Cell Host & Microbe  Volume 6, Issue 5, Pages (November 2009) DOI: /j.chom Copyright © 2009 Elsevier Inc. Terms and Conditions

2 Figure 1 Cowpox Inhibits MHC Class I Antigen Processing
CPXV12 acts as a TAP inhibitor to prevent peptide loading onto MHC class I in the ER. The CPXV203 protein contains an ER-retention signal that is instrumental in promoting retrieval and recycling of MHC class I from the Golgi. A portrait of Edward Jenner is shown above the model. Cell Host & Microbe 2009 6, DOI: ( /j.chom ) Copyright © 2009 Elsevier Inc. Terms and Conditions

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