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Efficacy and safety of antiscabietic agents: A systematic review and network meta- analysis of randomized controlled trials  Kunlawat Thadanipon, MD, Thunyarat.

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Presentation on theme: "Efficacy and safety of antiscabietic agents: A systematic review and network meta- analysis of randomized controlled trials  Kunlawat Thadanipon, MD, Thunyarat."— Presentation transcript:

1 Efficacy and safety of antiscabietic agents: A systematic review and network meta- analysis of randomized controlled trials  Kunlawat Thadanipon, MD, Thunyarat Anothaisintawee, MD, PhD, Sasivimol Rattanasiri, PhD, Ammarin Thakkinstian, PhD, John Attia, MD, PhD  Journal of the American Academy of Dermatology  Volume 80, Issue 5, Pages (May 2019) DOI: /j.jaad Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Systematic review flow diagram. RCT, Randomized controlled trial; WHO, World Health Organization. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Clustered ranking plot of antiscabietic agents showing their SUCRA values for highest probability of cure at 3-6 weeks versus SUCRA values for lowest probability of adverse events. Each symbol represents a group of treatments in each cluster. Treatments lying in right upper corner are associated with higher probability of cure and lower probability of adverse events. BenzylB, Benzyl benzoate; Herb, herbal medicine; OralIverm, oral ivermectin; Perm+OralIverm, combination permethrin plus oral ivermectin; SUCRA, surface under the cumulative ranking curve; SynPyrethr, synergized pyrethrins; TopIverm, topical ivermectin. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions

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