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Carbon dioxide management and the cerebral response to hemodilution during hypothermic cardiopulmonary bypass in dogs  David J Cook, MD, Umar S Boston,

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Presentation on theme: "Carbon dioxide management and the cerebral response to hemodilution during hypothermic cardiopulmonary bypass in dogs  David J Cook, MD, Umar S Boston,"— Presentation transcript:

1 Carbon dioxide management and the cerebral response to hemodilution during hypothermic cardiopulmonary bypass in dogs  David J Cook, MD, Umar S Boston, MD, Thomas A Orszulak, MD, Jared M Slater, BA  The Annals of Thoracic Surgery  Volume 72, Issue 4, Pages (October 2001) DOI: /S (01)

2 Fig 1 CDO2 and CMRO2 for O2 in pH-stat (n = 7) (left) and α-stat (n = 8) (right) groups. Values are mean ± SD. ∗p < 0.05 by repeated-measures ANOVA followed by Student-Newman-Keuls test. (CDO2 = cerebral oxygen delivery; CMRO2 = cerebral metabolic rate.) The Annals of Thoracic Surgery  , DOI: ( /S (01) )

3 Fig 2 The change in CBF versus Hgb concentration relationship in α-stat (n = 7) (dashed line) and pH-stat (n = 8) (solid line) groups. Curves were generated using an exponential model; R2 and line equations with slopes are shown. p = 0.89 by one-way ANOVA. (CBF = cerebral blood flow; Hgb = hemoglobin.) The Annals of Thoracic Surgery  , DOI: ( /S (01) )

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