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Clustering analysis of DTC-associated genes.

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Presentation on theme: "Clustering analysis of DTC-associated genes."— Presentation transcript:

1 Clustering analysis of DTC-associated genes.
Clustering analysis of DTC-associated genes. Heatmap of the 32 significant genes from the initial DTC analysis in 251 breast tumors, with genes and samples clustered separately. The color coding at the top indicates the breast cancer subtype. Below the heatmap, phenotypes are encoded such that black indicates a poorer value in terms of outlook. ER, estrogen receptor α; PgR, progesterone receptor. Stefan Werner et al. Cancer Discovery 2015;5: ©2015 by American Association for Cancer Research

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Table S1. Characteristics of breast tumor and normal breast tissue samples. Relevant characteristics of breast tumor and normal breast tissue samples analyzed.

Table S1. Characteristics of breast tumor and normal breast tissue samples. Relevant characteristics of breast tumor and normal breast tissue samples analyzed.
GeneGroupAnalysis 1.0.0-BetaCS Alejandro Quiroz-Zárate John Quackenbush lab

GeneGroupAnalysis BetaCS Alejandro Quiroz-Zárate John Quackenbush lab
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Date of download: 5/29/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Gene Expression Signatures, Clinicopathological Features,

Date of download: 5/29/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Gene Expression Signatures, Clinicopathological Features,
Table S1: The results of ER, PgR, and HER2 status in IHC testing and mRNA expression in the full Consortium population (N=389) HER2 statusER status PgR.

Table S1: The results of ER, PgR, and HER2 status in IHC testing and mRNA expression in the full Consortium population (N=389) HER2 statusER status PgR.
Figure 1. Correlation between estrogen receptor (ER), progesterone receptor (PR), and Ki-67 expression in primary breast tumors and synchronous axillary.

Figure 1. Correlation between estrogen receptor (ER), progesterone receptor (PR), and Ki-67 expression in primary breast tumors and synchronous axillary.
Fig. 2. Kaplan-Meier curves for survival in each breast cancer molecular subtype. Radiologic assessment in triple-negative breast cancer (A), HER2-positive.

Fig. 2. Kaplan-Meier curves for survival in each breast cancer molecular subtype. Radiologic assessment in triple-negative breast cancer (A), HER2-positive.
Figure 2. DNA methylation mediated MORT gene silencing is linked to luminal, receptor positive breast cancers. (A) MORT expression level plotted versus.

Figure 2. DNA methylation mediated MORT gene silencing is linked to luminal, receptor positive breast cancers. (A) MORT expression level plotted versus.
Multimodal Assessment of Estrogen Receptor mRNA Profiles to Quantify Estrogen Pathway Activity in Breast Tumors  Anita Muthukaruppan, Annette Lasham,

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Genes with Bimodal Expression Are Robust Diagnostic Targets that Define Distinct Subtypes of Epithelial Ovarian Cancer with Different Overall Survival 

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سرطان الثدي Breast Cancer

سرطان الثدي Breast Cancer
A B C Supplementary figure S7

A B C Supplementary figure S7
Distribution of mutations in different groups of genes, in cancer with extreme ML values. Distribution of mutations in different groups of genes, in cancer.

Distribution of mutations in different groups of genes, in cancer with extreme ML values. Distribution of mutations in different groups of genes, in cancer.
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Distribution of mutations in different groups of genes, in cancer with extreme ML values. Distribution of mutations in different groups of genes, in cancer.
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Heatmaps of the gene mutation distributions in oncogene‐signaling blocks for six representative cancer types. Heatmaps of the gene mutation distributions.

Heatmaps of the gene mutation distributions in oncogene‐signaling blocks for six representative cancer types. Heatmaps of the gene mutation distributions.
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Gene expression and genomic profiling reveal estrogen-independent ER transcriptional activity. Gene expression and genomic profiling reveal estrogen-independent.

Gene expression and genomic profiling reveal estrogen-independent ER transcriptional activity. Gene expression and genomic profiling reveal estrogen-independent.
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