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Fig. 3 Viral loads and viral DNA in anti-α4β7 antibody–treated rhesus macaques that initiated ART during chronic SIVmac251 infection (study 2). Viral loads.

Published byAnnis Matthews Modified over 5 years ago

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Presentation on theme: "Fig. 3 Viral loads and viral DNA in anti-α4β7 antibody–treated rhesus macaques that initiated ART during chronic SIVmac251 infection (study 2). Viral loads."— Presentation transcript:

1 Fig. 3 Viral loads and viral DNA in anti-α4β7 antibody–treated rhesus macaques that initiated ART during chronic SIVmac251 infection (study 2). Viral loads and viral DNA in anti-α4β7 antibody–treated rhesus macaques that initiated ART during chronic SIVmac251 infection (study 2). Plasma viral loads in macaques treated with (A) 50 mg/kg anti-α4β7 antibody (N = 7) or (B) sham IgG (N = 7). (C) Setpoint plasma viral loads on day 364. (D) Viral DNA levels in PBMCs, LNs, and CRs in macaques treated with 50 mg/kg anti-α4β7 antibody or sham IgG. (E) Viral DNA levels on day 63 in PBMCs, LNs, and CRs immediately before ART discontinuation. Plasma viral loads are shown as log SIV RNA copies/ml (limit of detection, 100 copies/ml). Viral DNA is shown as log SIV DNA copies per 1 × 106 cells (limit of detection, 3 copies/106 cells). Red lines indicate median values. Differences between groups were calculated by paired Student’s t tests. Peter Abbink et al. Science 2019;365: Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works

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