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Defining Incidence, Risk Factors, and Impact on Survival of Central Line-Associated Blood Stream Infections Following Hematopoietic Cell Transplantation.

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Presentation on theme: "Defining Incidence, Risk Factors, and Impact on Survival of Central Line-Associated Blood Stream Infections Following Hematopoietic Cell Transplantation."— Presentation transcript:

1 Defining Incidence, Risk Factors, and Impact on Survival of Central Line-Associated Blood Stream Infections Following Hematopoietic Cell Transplantation in Acute Myeloid Leukemia and Myelodysplastic Syndrome  Joshua Lukenbill, Lisa Rybicki, Mikkael A. Sekeres, Muhammad Omer Zaman, Alexander Copelan, Housam Haddad, Thomas Fraser, Megan J. DiGiorgio, Rabi Hanna, Hien Duong, Brian Hill, Matt Kalaycio, Ronald Sobecks, Brian Bolwell, Edward Copelan  Biology of Blood and Marrow Transplantation  Volume 19, Issue 5, Pages (May 2013) DOI: /j.bbmt Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Original and modified definition CLABSI after HCT (n = 73). Of 73 AML/MDS patients, 23 (32%) developed CLABSI under the standard NHSN definition, and 8 (11%) were diagnosed with MCLABSI. Median onset of OCLABSI was 9 days (range, 2 to 211) versus 12 days (range, 5 to 176) for MCLABSI. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 OCLABSI based on stem cell source and hematopoietic cord transplantation comorbidity index (HCT-CI). Four distinct risk groups for OCLABSI were found based on stem cell source (cord blood cells versus bone marrow/peripheral stem cells) and HCT-CI (high versus intermediate/low). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions


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