1. Characterizing an A*1101-restricted SSC-specific CD8+ cytotoxic T-cell clone.
Characterizing an A*1101-restricted SSC-specific CD8+ cytotoxic T-cell clone. A, avidity for SSC peptide was determined by cytotoxicity assay (E:T = 3:1). B, response to LMP2 expressed in A*1101-matched or -mismatched LCLs carrying EBV strains from Caucasian or Chinese populations was measured by IFNγ production. Target cells alone produced <100 pg/mL IFNγ. The responder:stimulator ratio = 1:10. Results show mean + SD and are representative of three separate experiments.
Yong Zheng et al. Cancer Immunol Res 2015;3:
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