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Pharmacodynamic modelling of β-lactam/β-lactamase inhibitor checkerboard data: illustration with aztreonam–avibactam  A. Chauzy, J. Buyck, B.L.M. de Jonge,

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Presentation on theme: "Pharmacodynamic modelling of β-lactam/β-lactamase inhibitor checkerboard data: illustration with aztreonam–avibactam  A. Chauzy, J. Buyck, B.L.M. de Jonge,"— Presentation transcript:

1 Pharmacodynamic modelling of β-lactam/β-lactamase inhibitor checkerboard data: illustration with aztreonam–avibactam  A. Chauzy, J. Buyck, B.L.M. de Jonge, S. Marchand, N. Grégoire, W. Couet  Clinical Microbiology and Infection  Volume 25, Issue 4, Pages 515.e1-515.e4 (April 2019) DOI: /j.cmi Copyright © 2018 The Authors Terms and Conditions

2 Fig. 1 Aztreonam MICs versus avibactam concentrations (mg/L) for 12 Enterobacteriaceae isolates. The circles represent the aztreonam MICs determined during one checkerboard experiment and the solid lines the individual aztreonam MICs predicted by the Emax model with baseline effect. Clinical Microbiology and Infection  , 515.e1-515.e4DOI: ( /j.cmi ) Copyright © 2018 The Authors Terms and Conditions


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