1. Expression of 20 genes significantly associated with reduced survivability in GBM is shown across 33 TCGA diseases.
Expression of 20 genes significantly associated with reduced survivability in GBM is shown across 33 TCGA diseases. Gene expression from each patient sample was converted to a z-score, and z-scores were recalculated across all diseases for each gene to show relative expression. Regions of the heatmap are circled to highlight genes with consistent higher expression (10th percentile >0.5) and previously published support for relevance to disease progression (cyan) or high expression without previously published support for disease progression (purple). Diseases are ranked by decreasing average expression and ribbon on the right is colored to indicate average expression per patient sample.
Andrea Shergalis et al. Pharmacol Rev 2018;70:
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