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Representative patient responses to ulixertinib.
Representative patient responses to ulixertinib. Longitudinal radiographic scans from a subset of patients who responded to ulixertinib are shown. A, A patient with gallbladder adenocarcinoma with a BRAF L485W mutation who experienced partial response in two lesions (green circles) over 12 weeks. B, A patient with glioblastoma multiforme with a BRAF V600E mutation who experienced a 64% reduction of their tumor (green circles) after 10 cycles of treatment with ulixertinib. Ryan J. Sullivan et al. Cancer Discov 2018;8: ©2018 by American Association for Cancer Research
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