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Published byAgnes Arntzen Modified over 5 years ago
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Monocytes from melanoma patients are unresponsive to TLR3 agonists.
Monocytes from melanoma patients are unresponsive to TLR3 agonists. Healthy volunteer leukocytes (A) and malignant melanoma patients' (MMP) leukocytes (B) stimulated with poly (I:C), dotted line and control, dashed line. Histogram of CD80 expression following 6-hour stimulation on monocytes (B). An increase in the expression of CD80 is not observed in patients with malignant melanoma following stimulation with poly (I:C). Representative histograms from a total of three independent experiments. Rahul Chavan et al. Cancer Immunol Res 2014;2: ©2014 by American Association for Cancer Research
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