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Fig. 4 Genomic and transcriptomic analysis of T

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1 Fig. 4 Genomic and transcriptomic analysis of T
Fig. 4 Genomic and transcriptomic analysis of T. thermosaccharolyticum strain TG57. Genomic and transcriptomic analysis of T. thermosaccharolyticum strain TG57. (A) Genome overview of strain TG57 with previously genome-sequenced isolates [C. acetobutylicum ATCC 824 (accession no. AE001437), C. beijerinckii NCIMB 8052 (accession no. CP000721), Clostridium sp. MF28 (accession no. CP014331), and T. thermosaccharolyticum DSM 571 (accession no. CP002171) ] deposited in the GenBank database. (B) Circos plot represents similarity between strain TG57 and C. acetobutylicum ATCC 824 based on gene sequence and biological annotation. Track (green) on the left, strain TG57; track (black) on the right, strain ATCC 824. Number represents CDS. The links are color-coded by similarity. Red, 100% similarity; blue, 0% similarity. (C) Transcriptomic analysis of strain TG57. Tracks from the inside to outside: tracks 1 and 2, the transcription levels of all genes in culture on xylan and cellulose; track 3, cellulosome genes (red, forward strand; blue, reverse strand); track 4, genes for carbohydrates in glycoside hydrolase family (green, forward strand; orange, reverse strand); track 5, CDS (red, forward strand; blue, reverse strand); track 6, genome sequence of T. thermosaccharolyticum TG57. (D) Butanol synthesis and NADH (reduced form of nicotinamide adenine dinucleotide)/NADPH (reduced form of nicotinamide adenine dinucleotide phosphate) regenerations in T. thermosaccharolyticum TG57. Tinggang Li et al. Sci Adv 2018;4:e Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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