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Bringing Optogenetics to the Synapse

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Presentation on theme: "Bringing Optogenetics to the Synapse"— Presentation transcript:

1 Bringing Optogenetics to the Synapse
Andreas Reiner, Joshua Levitz, Ehud Isacoff  Neuron  Volume 79, Issue 2, Pages (July 2013) DOI: /j.neuron Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 Optical Ablation of Neurotransmitter Release with InSynC
(A) Targeting of miniSOG to a subset of presynaptic inputs (green fibers). (B) Light-induced singlet oxygen formation inhibits neurotransmitter release at terminals expressing miniSOG at vesicles. (C) Long-lasting, but reversible, inhibition of neurotransmission at a subset of presynaptic terminals in response to illumination with 480 nm light. Neuron  , DOI: ( /j.neuron ) Copyright © 2013 Elsevier Inc. Terms and Conditions

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