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Iron Overload in Patients with Acute Leukemia or MDS Undergoing Myeloablative Stem Cell Transplantation  Philippe Armand, Haesook T. Kim, Joanna Rhodes,

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Presentation on theme: "Iron Overload in Patients with Acute Leukemia or MDS Undergoing Myeloablative Stem Cell Transplantation  Philippe Armand, Haesook T. Kim, Joanna Rhodes,"— Presentation transcript:

1 Iron Overload in Patients with Acute Leukemia or MDS Undergoing Myeloablative Stem Cell Transplantation  Philippe Armand, Haesook T. Kim, Joanna Rhodes, Marie-Michele Sainvil, Corey Cutler, Vincent T. Ho, John Koreth, Edwin P. Alyea, Doreen Hearsey, Ellis J. Neufeld, Mark D. Fleming, Hanno Steen, Damon Anderson, Raymond Y. Kwong, Robert J. Soiffer, Joseph H. Antin  Biology of Blood and Marrow Transplantation  Volume 17, Issue 6, Pages (June 2011) DOI: /j.bbmt Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Distribution of pretransplantation serum ferritin and liver iron content (estimated by MRI). (A) Serum ferritin (in ng/mL); (B) Liver iron content (in mg/g dry weight). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Relationship between liver iron content, ferritin, and transfusion history. (A) Scatterplot of liver iron content (in mg/g dry weight) versus serum ferritin (in ng/mL); (B) Liver iron content versus adjusted serum ferritin (see text for details); (C) Liver iron content versus number of prior red cell units transfused. Dotted lines were fit to data using a cubic spline. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions


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