1. Appearance of Focal Liver Lesions Using Contrast-Enhanced Magnetic Resonance Imaging Using Gadofosveset Trisodium, an Intravascular (Blood-Pool) Contrast Agent: A Pictorial Essay 
H.M.C. Cheung, MD, C. Law, MD, MPH, M. Shoichet, MD, P.J. Karanicolas, MD, PhD, N. Coburn, MD, MPH, L. Milot, MD, MSc 
Canadian Association of Radiologists Journal 
Volume 67, Issue 3, Pages (August 2016)
DOI: /j.carj
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2. Figure 1
Cavernous hepatic hemangioma with gadofosveset-enhanced magnetic resonance imaging in (A) arterial, (B) portal venous, and (C) 10-minute delayed phase imaging demonstrates early peripheral discontinuous enhancement with progressive fill-in.
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3. Figure 2
Focal nodular hyperplasia with gadofosveset-enhanced magnetic resonance imaging in (A) arterial, (B) portal venous, and (C) 10-minute delayed phase imaging demonstrates homogeneous arterial enhancement that fades to background liver on portal venous and delayed phase imaging. The central scar is hypoenhancing on arterial phase with progressive enhancement on delayed phases.
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4. Figure 3
Hepatic adenoma with gadofosveset-enhanced magnetic resonance imaging in (A) arterial, (B) portal venous, and (C) 10-minute delayed phase imaging demonstrates slight arterial enhancement with washout of contrast on portal venous and delayed phase imaging.
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5. Figure 4
Hepatocellular carcinoma with gadofosveset-enhanced magnetic resonance imaging in (A) arterial, (B) portal venous, and (C) 10-minute delayed phase imaging demonstrates arterial enhancement with washout of contrast on portal venous and delayed phase imaging. Note the presence of a tumour capsule.
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6. Figure 5
Cholangiocarcinoma with gadofosveset-enhanced magnetic resonance imaging (MRI) in (A) arterial and (B) 10-minute delayed phase imaging and with gadobutrol-enhanced MRI in (C) 10-minute delayed phase imaging. There is rim enhancement on arterial phase imaging with progressive central enhancement on delayed phase imaging and associated capsular retraction. Note that the degree of central enhancement on delayed phase imaging appears greater with gadobutrol than with gadofosveset.
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7. Figure 6
Liver metastasis from colorectal cancer with gadofosveset-enhanced magnetic resonance imaging (MRI) in (A) arterial and (B) 10-minute delayed phase imaging and with gadobutrol-enhanced MRI in (C) 10-minute delayed phase imaging. The lesion appears hypoenhancing on all phases with gadofosveset. There is central enhancement seen on delayed phase imaging with gadobutrol that is less pronounced with gadofosveset.
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8. Figure 7
Liver metastasis from pancreatic adenocarcinoma with gadofosveset-enhanced magnetic resonance imaging (MRI) in (A) arterial and (B) 10-minute delayed phase imaging and with gadobutrol-enhanced MRI in (C) 10-minute delayed phase imaging. There is continuous rim enhancement on arterial phase that persists in the delayed phases.
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9. Figure 8
Multiple liver metastases from breast cancer with gadofosveset-enhanced magnetic resonance imaging (MRI) in the (A) arterial and (B) 10-minute delayed phase imaging and with gadobutrol-enhanced MRI in (C) 10-minute delayed phase imaging. There is rim enhancement of the metastases. Enhancement is less pronounced on delayed phase imaging with gadofosveset than with gadobutrol.
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10. Figure 9
Liver metastasis from renal cell carcinoma with gadofosveset-enhanced magnetic resonance imaging (MRI) in the (A) arterial and (B) 10-minute delayed phase imaging and with gadobutrol-enhanced MRI in (C) 10-minute delayed phase imaging. There is arterial enhancement with perisistent enhancement in delayed phase imaging in keeping with a hypervascular metastasis.
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11. Figure 10
Multiple liver metastases from a carcinoid tumour with gadofosveset-enhanced magnetic resonance imaging (MRI) in the (A) arterial and (B) 10-minute delayed phase imaging and with gadobutrol-enhanced MRI in (C) 10-minute delayed phase imaging. There is arterial enhancement with persistent enhancement in delayed phase imaging. Note that there is a greater degree of enhancement on delayed phase imaging with gadofosveset than with gadobutrol.
Canadian Association of Radiologists Journal  , DOI: ( /j.carj )
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