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PKC Defends Crown Against Munc13

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1 PKC Defends Crown Against Munc13
Mark Palfreyman, Erik M. Jorgensen  Neuron  Volume 54, Issue 2, Pages (April 2007) DOI: /j.neuron Copyright © 2007 Elsevier Inc. Terms and Conditions

2 Figure 1 Codependent Targets of DAG
DAG activation of PKC has a long-acting effect by phosphorylating Munc18. DAG activation of Munc13 is short-acting. Together, phosphoMunc18 and Munc13 can stimulate the probability of vesicle fusion (right). The interaction of Munc18 and Munc13 shown is functional and is not known to be direct. Neuron  , DOI: ( /j.neuron ) Copyright © 2007 Elsevier Inc. Terms and Conditions

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