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The activation of PKC-δ and JNK1 is essential for doxorubicin-induced senescence. The activation of PKC-δ and JNK1 is essential for doxorubicin-induced.

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Presentation on theme: "The activation of PKC-δ and JNK1 is essential for doxorubicin-induced senescence. The activation of PKC-δ and JNK1 is essential for doxorubicin-induced."— Presentation transcript:

1 The activation of PKC-δ and JNK1 is essential for doxorubicin-induced senescence.
The activation of PKC-δ and JNK1 is essential for doxorubicin-induced senescence. MCF7 cells were treated with rottlerin or SP at the indicated times following doxorubicin treatment, and SA-β-Gal activity was analyzed 6 d later. A. Intervals when rottlerin affected doxorubicin-induced senescence. B. Intervals when SP affected doxorubicin-induced senescence. Sae Lo Oom Lee et al. Mol Cancer Res 2009;7: ©2009 by American Association for Cancer Research

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