1. Samia Metwally, DVM, PhD (FAO)
Criteria for Selection and Responsibilities of Regional Leading Laboratory
Samia Metwally, DVM, PhD (FAO)
Gregorio Torres (OIE)

2. Lab Network- One Tool of the Global Strategy
Develop, maintain and strengthen an integrated international, regional and national network of laboratories that can respond quickly to needs for rapid and accurate testing, and timely notification
Gain more intelligence on FMD virus strains circulating in regions
Improve vaccine selection – supporting both endemic and free countries and essential to progressive control
Enhance diagnostic capability for other priority diseases in the region

3. FMD Lab and Epidemiology Networks
Diagnostic analysis
Surveillance, monitoring, and disease tracking

4. OIE-FAO FMD Ref Lab Network FMD Seven Regional Virus Pools3 1 2 4 5 7 6
WRL- FMD Reference lab/centers

5. Current Status of FMD Reference Lab Network
OIE/FAO FMD reference lab network
One world and twelve reference labs/centers
Annual meeting, training and work plans
Provide diagnostic services
Share disease status information in respective regions
Create a comprehensive FMD report on an annual basis

6. Diagnostics Requirements for PCP Stages
Implement
risk-based control 2 1
Identify risk and control options
Maintain zero circulation and incursions 4
Control strategy to eliminate circulation 3
Maintain zero circulation; withdraw vaccination 5
Surv & early detection
Quality Ctr & Assurance
VI, characterization, molecular dx, vaccine matching
(Biocontainment)
Monitoring
Typing and SP ELISA
VP1 sequencing
Screening
ELISA /PCR
In country
Region/reference

7. Surveillance Approaches
Random or non-random approaches
Virological Methods
Serological Methods
Clinical Methods

8. Regional Leading Laboratory Selection Criteria
Creditability and acceptance by countries of the region
Commitment from the government to support and sustain lab functions as described in the terms of reference
Lab capacity and capability to perform diagnostics for FMD/PPR/other TADs
Capability to handle exotic viruses from other countries in the region
Certification to ship and receive international diagnostic samples
Participated or willingness to take part in OIE twinning program
Keen interest to be designated as a FAO/OIE reference center
Established link with FMD reference laboratorty
Maintain good performance on proficiency testing carried by reference center

9. Regional Leading Laboratory Terms of Reference
Produces diagnostic reagents, SOPs and protocols
Provides training to national laboratories using train the trainers approach
Coordinates proficiency testing for the region (limited to screening tests)
Receives and processes samples for diagnostics from countries of the region
Ships samples to FAO/OIE reference centers for full characterization
Ensures and assist in regional procurement of essential diagnostic reagents for emergency release
Participates in regional laboratory network activities (potential leader)
Links with the regional epidemiology network

10. Regional Leading Laboratory Procedures for Nomination
Acceptance by countries of the region
Meeting the selection criteria
Government official commitment to support terms of reference/responsibilities

11. Thank you for your attention