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Volume 82, Issue 1, Pages (July 2012)

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1 Volume 82, Issue 1, Pages 84-89 (July 2012)
Bioavailable vitamin D is more tightly linked to mineral metabolism than total vitamin D in incident hemodialysis patients  Ishir Bhan, Camille E. Powe, Anders H. Berg, Elizabeth Ankers, Julia B. Wenger, S. Ananth Karumanchi, Ravi I. Thadhani  Kidney International  Volume 82, Issue 1, Pages (July 2012) DOI: /ki Copyright © 2012 International Society of Nephrology Terms and Conditions

2 Figure 1 Total vs. bioavailable 25-hydroxyvitamin D (25(OH)D) and serum calcium. Total levels of 25(OH)D (left panel) demonstrated no association with serum calcium levels (corrected for albumin), whereas bioavailable 25(OH)D levels (right panel) were positively associated with serum calcium. Kidney International  , 84-89DOI: ( /ki ) Copyright © 2012 International Society of Nephrology Terms and Conditions

3 Figure 2 Total vs. bioavailable 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone (PTH). After adjustment for age, gender, race, and survival status at 1 year, bioavailable 25(OH)D was significantly negatively associated with PTH levels, whereas total 25(OH)D demonstrated no association with PTH. Kidney International  , 84-89DOI: ( /ki ) Copyright © 2012 International Society of Nephrology Terms and Conditions

4 Figure 3 Sample selection. 25-Hydroxyvitamin D (25(OH)D) and 1,25-dihydroxyvitamin D (1,25(OH)2D) were previously measured as part of a case–control study within the Accelerated Mortality on Renal Replacement (ArMORR) cohort.19 Equal numbers of cases (subjects who died within their first year on dialysis) and controls were randomly selected from each racial group. Kidney International  , 84-89DOI: ( /ki ) Copyright © 2012 International Society of Nephrology Terms and Conditions


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