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DegrAAAded into Silence

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Presentation on theme: "DegrAAAded into Silence"— Presentation transcript:

1 DegrAAAded into Silence
Elizabeth H. Bayne, Sharon A. White, Robin C. Allshire  Cell  Volume 129, Issue 4, Pages (May 2007) DOI: /j.cell Copyright © 2007 Elsevier Inc. Terms and Conditions

2 Figure 1 Silencing Heterochromatin in Fission Yeast
Noncoding RNA transcripts originating from heterochromatin repeats, or transgene insertions within heterochromatin, may be polyadenylated by Cid14. The transcript may be polyadenylated directly upon termination of transcription, or alternatively transcripts may be first sliced by Ago1 and then polyadenylated by Cid14. This may “mark” the transcript for degradation and/or processing via the RNAi machinery, RDRC/Dcr1, or the exosome. Cell  , DOI: ( /j.cell ) Copyright © 2007 Elsevier Inc. Terms and Conditions

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