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Published byLéonard Legaré Modified over 5 years ago
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Characterizing Virological Suppression in Today's Treatment Paradigm
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Key Objectives of This Program
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Virological Suppression Represents Success for the Patient
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Definitions of Virological Suppression
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What Constitutes Virological Failure?
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How Can We Limit Virological Failure?
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How Do We Define Success With Highly Efficacious Treatment?
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Defining Success in Treatment-Naive Patients
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GEMINI-1 and -2 Phase 3 Study Designs
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GEMINI-1 and -2 Phase 3 Primary Outcomes
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GEMINI-1 and -2: Analysis of Participants With TND Over Baseline VL for 2DR and 3DR
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Considerations for Clinicians
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FLAIR: Long-Acting Cabotegravir + Rilpivirine for HIV Maintenance
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FLAIR: Results for Primary and Secondary Endpoints
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FLAIR: Injection Site Reactions
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FLAIR: Patient Preference Survey
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FLAIR: Patients Who Experienced Virologic Failure CAB LA + RPV LA Arm
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Clinical Case: 48-Year-Old Man
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Clinical Case: 48-Year-Old Man (cont)
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Clinical Case: 48-Year-Old Man (cont)
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Considerations for Clinicians (cont)
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Clinical Case: 46-Year-Old Woman
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Clinical Case: 46-Year-Old Woman (cont)
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SWORD-1 and -2: Analysis of Viral Replication for 2DR vs 3DR
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Clinical Case: 46-Year-Old Woman (cont)
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PARTNER Study
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PARTNER: Key Conclusions
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Communicating With Patients Regarding Virological Suppression
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Concluding Remarks
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Abbreviations
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Abbreviations (cont)
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Abbreviations (cont)
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