1. Paradigm for the cycle of precision vaccinology.
Paradigm for the cycle of precision vaccinology. Development of precision vaccines may include systems biology analysis of biosamples from clinical trials to define molecular pathways that correlate with immunogenicity, thereby generating new hypotheses; use of in vitro systems for hypothesis testing; and characterization of population-specific responses, thereby informing use of appropriate animal models and targeted clinical trials.
Francesco Borriello et al. mSphere 2018; doi: /mSphere