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Modularized Functions of the Fanconi Anemia Core Complex

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Presentation on theme: "Modularized Functions of the Fanconi Anemia Core Complex"— Presentation transcript:

1 Modularized Functions of the Fanconi Anemia Core Complex
Yaling Huang, Justin W.C. Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata, Junjie Chen, Lei Li  Cell Reports  Volume 14, Issue 11, Pages (March 2016) DOI: /j.celrep Copyright © 2016 The Authors Terms and Conditions

2 Figure 1 Various Sensitivities of FA Knockout Mutants Identify the FA Core Complex Catalytic Module Cell Reports  , DOI: ( /j.celrep ) Copyright © 2016 The Authors Terms and Conditions

3 Figure 3 The A-G-20 and C-E-F Modules Exhibit Nonredundant Functions in the Chromatin Recruitment of the FA Core Complex and Resistance to Crosslink Damage Cell Reports  , DOI: ( /j.celrep ) Copyright © 2016 The Authors Terms and Conditions

4 Figure 4 FANCM Functions Epistatically with the C-E-F Module in FA Core Complex Chromatin Association Cell Reports  , DOI: ( /j.celrep ) Copyright © 2016 The Authors Terms and Conditions

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