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Figure 1. PRISMA-style literature-search diagram: schematic outlining structured literature search completed on August ... Figure 1. PRISMA-style literature-search.

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Presentation on theme: "Figure 1. PRISMA-style literature-search diagram: schematic outlining structured literature search completed on August ... Figure 1. PRISMA-style literature-search."— Presentation transcript:

1 Figure 1. PRISMA-style literature-search diagram: schematic outlining structured literature search completed on August ... Figure 1. PRISMA-style literature-search diagram: schematic outlining structured literature search completed on August 4, Separate literature searches were performed for the ADHD and sleep deprivation literatures, respectively, in both Pubmed and PsychInfo databases. For the ADHD literature, our search items were as follows: [(ADHD OR “attention deficit hyperactivity disorder”) AND (fMRI OR “magnetic resonance imaging”)]. For sleep deprivation, we used the analogous search: [(“sleep deprivation” OR “sleep restriction” OR “sleep loss”) AND (fMRI or “magnetic resonance imaging”)]. Results were then collapsed and overlapping articles removed before being screened for inclusion as indicated in the article. Supplementary Material includes complete bibliographies for each of the four final inclusion categories (TSD > Rested; Rested > TSD; ADHD > HC; HC > ADHD). Unless provided in the caption above, the following copyright applies to the content of this slide: © Sleep Research Society Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( Sleep, Volume 42, Issue 3, 12 December 2018, zsy251, The content of this slide may be subject to copyright: please see the slide notes for details.

2 Figure 2. Patterns of overlapping and distinct decreases in brain activity between ADHD and sleep deprivation. (A) ... Figure 2. Patterns of overlapping and distinct decreases in brain activity between ADHD and sleep deprivation. (A) Overlap (yellow) in patterns of decreased brain activity between the ADHD (green) and sleep deprivation (red) literatures are presented on representative axial brain sections. (B) Areas where hypoactivations were significantly different between ADHD and sleep deprivation. Clusters with greater hypoactivation in sleep deprivation are shown in red; areas where hypoactivation was significantly greater for ADHD are shown in green (none reached statistical significance). First-level clusters were formed using a threshold of p < .005, k = 20 mm<sup>3</sup>, and difference analyses conducted using permutation-testing (10,000 permutations, FDR q < .05, k = 20mm [3]). Unless provided in the caption above, the following copyright applies to the content of this slide: © Sleep Research Society Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( Sleep, Volume 42, Issue 3, 12 December 2018, zsy251, The content of this slide may be subject to copyright: please see the slide notes for details.

3 Figure 3. Patterns of distinct increases in brain activity between ADHD and sleep deprivation. Presented as in Figure ... Figure 3. Patterns of distinct increases in brain activity between ADHD and sleep deprivation. Presented as in Figure 1B. Areas where hyperactivations were significantly different between ADHD and sleep deprivation. Clusters with greater hyperactivation in sleep deprivation are shown in red; areas where hyperactivation was significantly greater for ADHD are shown in green (none reached statistical significance). First-level clusters were formed using a threshold of p < .005, k = 20 mm<sup>3</sup>, and difference analyses conducted using permutation testing ( permutations, FDR q < .05, k = 20mm [3]). Unless provided in the caption above, the following copyright applies to the content of this slide: © Sleep Research Society Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( Sleep, Volume 42, Issue 3, 12 December 2018, zsy251, The content of this slide may be subject to copyright: please see the slide notes for details.

4 Figure 4. Heuristic of convergence and divergence of neuroanatomy in sleep deprivation and ADHD. Summary of main ... Figure 4. Heuristic of convergence and divergence of neuroanatomy in sleep deprivation and ADHD. Summary of main meta-analysis conjunction analysis, identifying simultaneous decreases in activation in executive function brain networks. However, sleep deprivation and not ADHD was associated with a compensatory thalamic arousal. Unless provided in the caption above, the following copyright applies to the content of this slide: © Sleep Research Society Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( Sleep, Volume 42, Issue 3, 12 December 2018, zsy251, The content of this slide may be subject to copyright: please see the slide notes for details.

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