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Published byInger Overgaard Modified over 5 years ago
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ALK Status Testing in Non–Small-Cell Lung Carcinoma by FISH on ThinPrep Slides with Cytology Material Eugen C. Minca, MD, PhD, Christopher P. Lanigan, MS, Jordan P. Reynolds, MD, Zhen Wang, MD, PhD, Patrick C. Ma, MD, Joseph Cicenia, MD, Francisco A. Almeida, MD, Nathan A. Pennell, MD, Raymond R. Tubbs, DO Journal of Thoracic Oncology Volume 9, Issue 4, Pages (April 2014) DOI: /JTO Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions
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FIGURE 1 Representative images of non–small-cell lung carcinoma positive for ALK rearrangements by ThinPrep-FISH showing a typical positive pattern (A, ThinPrep-Papanicolaou 1000×; B, ThinPrep-FISH 1000×), and positive for ALK expression by D5F3-IHC on the paraffin cytoblock (C, hematoxylin and eosin 400×; D, D5F3-IHC, 400×). FISH, fluorescence in situ hybridization; ALK, anaplastic lymphoma kinase; IHC, immunohistochemistry. Journal of Thoracic Oncology 2014 9, DOI: ( /JTO ) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions
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