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Staged excision for lentigo maligna and lentigo maligna melanoma: A retrospective analysis of 117 cases  Carole Hazan, MD, Stephen W. Dusza, MPH, Ruby.

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Presentation on theme: "Staged excision for lentigo maligna and lentigo maligna melanoma: A retrospective analysis of 117 cases  Carole Hazan, MD, Stephen W. Dusza, MPH, Ruby."— Presentation transcript:

1 Staged excision for lentigo maligna and lentigo maligna melanoma: A retrospective analysis of 117 cases  Carole Hazan, MD, Stephen W. Dusza, MPH, Ruby Delgado, MD, Klaus J. Busam, MD, Allan C. Halpern, MD, Kishwer S. Nehal, MD  Journal of the American Academy of Dermatology  Volume 58, Issue 1, Pages (January 2008) DOI: /j.jaad Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Clinical orientation: biopsy-proven lentigo maligna with 5-mm excision margin marked. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Excised tissue orientation: tumor debulking is located in center; it is surrounded by 4 quarters of peripheral margin arranged in clockwise fashion with suture orientation; deep and outer side margins represent true surgical margins. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Histologic sectioning: central row contains serial sections of tumor debulking; serial sections of peripheral margins are arranged clockwise with suture orientation; deep and outer surgical margins are inked black. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 Histologic evaluation of tumor debulking: residual melanoma in situ with hematoxylin and eosin (10X) (A) and immunostain with A103 (anti-Melan-A) (B). Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

6 Fig 5 Histologic evaluation of surgical margins. A, Perpendicular/vertical section with melanoma in situ extending to inked side margin (positive margin). B, Perpendicular/vertical section with no melanocytic neoplasm seen (negative margin). (A and B, Hematoxylin-eosin stain; original magnification: ×20.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

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