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CD137 Expression Identifies Leukemia Specific CTL after in Vitro Priming of Cord Blood T Cells Previously Expanded By CD3/CD28 Co-Stimulation  Jeyaraj.

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Presentation on theme: "CD137 Expression Identifies Leukemia Specific CTL after in Vitro Priming of Cord Blood T Cells Previously Expanded By CD3/CD28 Co-Stimulation  Jeyaraj."— Presentation transcript:

1 CD137 Expression Identifies Leukemia Specific CTL after in Vitro Priming of Cord Blood T Cells Previously Expanded By CD3/CD28 Co-Stimulation  Jeyaraj Antony, Ph.D, Xiaohua Chen, Ph.D, Paul Szabolcs, MD  Biology of Blood and Marrow Transplantation  Volume 20, Issue 2, Pages S258-S259 (February 2014) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure 1 Representative dot plot showing the expression of CD137 on CTL before and after sort Biology of Blood and Marrow Transplantation  , S258-S259DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Figure 2 The cytotoxicity of CTL generated against IM9 cells using expanded CBT and IL 15 resides in CD137+ cells (mean ± SEM, n=5) Biology of Blood and Marrow Transplantation  , S258-S259DOI: ( /j.bbmt ) Copyright © Terms and Conditions

4 Figure-3 Oligoclonal expansion of TCR Vβ 7, Vβ 5.1 and Vβ 21 observed in isolated CD137+ cells. Biology of Blood and Marrow Transplantation  , S258-S259DOI: ( /j.bbmt ) Copyright © Terms and Conditions

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