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Variations in beta and alpha diversity of gut microbiome bacterial communities in relation to presence of Blastocystis. Variations in beta and alpha diversity of gut microbiome bacterial communities in relation to presence of Blastocystis. (A) Principal-component analysis (PCoA) ordination of variation in beta diversity of human gut bacterial communities based on Bray-Curtis dissimilarities among fecal samples. Colors represent the presence of Blastocystis in gut microbial communities (red for negative and blue for positive), and arrows represent the significant (P < 0.001) correlations between PCoA axes versus the relative abundances of bacterial genera in communities. (B and C) Shannon diversity (B) and Chao1 estimated richness (C) display differences in alpha diversity. Significant differences are shown by P values of Mann-Whitney tests for comparison between 2 groups. (D) Relative abundances of the 10 most abundant bacterial OTUs relative to the presence of Blastocystis. Significant differences are shown, calculated by DESeq2 (Wald test plus FDR). M. E. Nieves-Ramírez et al. mSystems 2018; doi: /mSystems
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