1. Eosinophil progenitor levels are increased in patients with active pediatric eosinophilic esophagitis 
David W. Morris, MD, Emily M. Stucke, BA, Lisa J. Martin, PhD, J. Pablo Abonia, MD, Vincent A. Mukkada, MD, Philip E. Putnam, MD, Marc E. Rothenberg, MD, PhD, Patricia C. Fulkerson, MD, PhD 
Journal of Allergy and Clinical Immunology 
Volume 138, Issue 3, Pages e5 (September 2016)
DOI: /j.jaci
Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
A, Median absolute EoP levels in patients with active versus inactive EoE are shown. For all box plots, boxes indicate 25th-75th percentiles, whiskers indicate minimum to maximum values, all points are shown, and each point represents an individual patient. B, Median absolute EoPs correlate with peak esophageal eosinophil count (Spearman). C, Receiver operating characteristic analysis of the ability of EoP levels to discriminate between patients with and without active EoE. The solid diagonal line indicates values that have no discriminatory value. AUC, Area under the curve. D, Comparison of median EoP levels in patients with active EoE divided into 2 groups, restricted diet (food trials) versus unrestricted diet, is shown. E, Median values of peak esophageal eosinophils in patients with active EoE divided into 2 groups, restricted diet (food trials) versus unrestricted diet, are shown.
Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci )
Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig E1
Gating strategy for EoPs. Live CD45RA− cells were gated for CD34+ events. This population was gated for CD38 and CD125 (IL-5 receptor α), with double-positive events being considered EoPs. EoP levels are expressed in absolute numbers per milliliter of blood. SSC, Side scatter.
Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci )
Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4. Fig E2
Median absolute EoPs per milliliter of blood stratified by patient age are shown. Significance levels are indicated, and bars span the different groups.
Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci )
Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5. Fig E3
Median of EoPs of patients with EoE with and without asthma (A), allergic rhinitis (B), or atopic dermatitis (C). Boxes indicate 25th-75th percentiles, whiskers indicate minimum to maximum values, all values are shown, and each circle or square represents an individual patient.
Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci )
Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6. Fig E4
Spearman correlation between peripheral blood eosinophils (absolute count per microliter) and peripheral blood EoPs (absolute count per milliliter) is shown.
Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci )
Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions