1. OATech+ Network: Funding Review
Leanne Sawle

2. Budget £741,331 £238,779 consumables £227,552 travel
Budget for activities and projects
£741,331
£238,779 consumables
£227,552 travel
£275,000 research pot

3. General Spending
Spent Pending
£69, £4,568.86

4. Commitments – Network projects (80% fEC)
To develop tools for patient stratification in OA
To identify the characteristics of ‘pain’ and ‘structural damage’ characteristics in OA
Nidhi Sofat (Clinical Applications), St George’s
Developing tools for Patient Stratification in Osteoarthritis
£86,774 (1/10/18 – 30/9/19)
Mark Elliott (Data and Data Analytics), Warwick
OA Datasets Scoping Project
£62,273 (28/1/19- 27/9/19)
Feasibility of creating an OA Datasets resource
Alan Turing Institute call for data sets and application challenges (clinical gait analysis)

5. Commitments – Network projects (80% fEC)
Richard Jones (Lifestyle Interventions), Salford (also involving David Hamilton, Edinburgh)
The role of technology and lifestyle interventions in osteoarthritis
£46,233
Systematic review

6. Commitments – Network projects (80% fEC)
Debbie Mason + Alison McGregor (high-level evidence and impact), Cardiff
Systematic review to define the higher level evidence in osteoarthritis research that can be used to develop an impact toolkit
£57,015 (1/1/19-30/6/19)
Imaging group /Cathy Holt, Cardiff
Development of MRI protocols to create 3D computer models and structural imaging for model-based image registration. Development of in vivo dynamic biplane X-ray protocols £60,585 (1/7/19)

7. Commitments – Network projects (Sandpit awards)
David Williams, Cardiff (involving H. Markides, Birmingham)
Development of a quantitative MRI phantom for knee tissue
£19,086 (1/7/ /6/20)
Debbie Mason and David Hamilton (Cardiff and Edinburgh)
We don’t care how much it hurts (but we do care about nocioception)
£18,750 (1/8/ /1/20)
Developing a cartilage phantom for assessing cartilage composition using quantitative MR sequences
Wearable sensors as objective measures of nocioception

8. Commitments – Network activities
3 x 3K awards made
Theme leads / PI
ECR placements
Jim Richards (Next Generation of Researchers in OA)
£12,000
Pump-priming projects
Martin Knight (Biomechanics and Mechanobiology)
£50,000
Hackathon
Mark Elliott (Data and Data Analytics)
£25,000
Awards of up to 10K to be announced

9. Commitments – Network activities
Theme leads / PI
Focus meeting (consensus statement development)
Richard Jones (Lifestyle Interventions)
£10,000
Future Imaging working group
Imaging group /Cathy Holt
£2,824.4
a) Importance of activity measurement pre‐post TKR
b) Assessing quality of movement?
c) Priorities for technological
advancements measurement of activity?
d) Opportunities for multi‐centre research
PDRA to start 1/7/19

10. Commitments – Network activities
UK imaging experts workshop
Imaging group /Cathy Holt
£4,336.6
Modelathon (EPSRC MultiSim and OATech)
Experimental and Predictive Modelling group
£11,000
Clinical problems webpage
Martin Knight (Biomechanics and Mechanobiology)
£5,000
Identify key dissemination routes
Subject-specific modelling of the human knee to chose the best treatment among different types (total knee replacement, condyle resurfacing, osteochondral plugs)
Clinicians can pose “real world” problems

11. Commitments – Network activities
Engagement events in biomechanics and mechanobiology
Martin Knight (Biomechanics and Mechanobiology)
£25,000
3-day sandpit
Experimental and Predictive Modelling group
£26,000
Public engagement pots of money
50K award for gathering preliminary data on multi-scale modelling of primary OA including pain

12. Commitments – General Health economics support £5,000
ECR Working group and events
Jim Richards (Next Generation of Researchers in OA)
£6,000
PPI and engagement
Network wide

13. Commitments – General Sandpit Biomechanics and Mechanobiology £12,450
OATech+ Network Conference (2020)
For the entire Network and interested parties
£50,000

14. Final Review (May 2019)
Total Spending + Commitments
(including modelling awards 50K)
£724,935.93
Remaining Budget
£16,395
Project end date 30/09/2020

15. Future Plans Data repository Network legacy
Data sets are being gathered (750 volunteers)