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Volume 66, Issue 1, Pages (July 2004)

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Presentation on theme: "Volume 66, Issue 1, Pages (July 2004)"— Presentation transcript:

1 Volume 66, Issue 1, Pages 262-267 (July 2004)
Up-regulation of hepatic Acyl CoA: Diacylglycerol acyltransferase-1 (DGAT-1) expression in nephrotic syndrome  Nosratola D. Vaziri, Choong H. Kim, Dennis Phan, Sara Kim, Kaihui Liang  Kidney International  Volume 66, Issue 1, Pages (July 2004) DOI: /j x Copyright © 2004 International Society of Nephrology Terms and Conditions

2 Figure 1 Hepatic microsomal total DGAT activity and free fatty acid concentration in the nephrotic (NS) and normal control (CTL) groups. DGAT activity is presented as nmol of trioleoylglycerol/mg protein/hour. N = 6 in each group, *P < 0.05. Kidney International  , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions

3 Figure 2 Mean normalized DGAT-1 gene expression and DGAT-1 activity in the liver of nephrotic (NS) and normal control (CTL) groups. 18s rRNA was used as reference for DGAT-1 gene expression. N = 6 in each group, *P < 0.05. Kidney International  , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions

4 Figure 3 Mean normalized DGAT-2 gene expression and DGAT-2 activity in the liver of nephrotic (NS) and normal control (CTL) groups. 18s rRNA was used as reference for DGAT-2 gene expression. N = 6 in each group. Kidney International  , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions

5 Figure 4 Correlations between hepatic microsomal free fatty acid concentration and DGAT activity in the nephrotic (○) and normal control (•) groups. Kidney International  , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions


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