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PREDICTION OF NOSOCOMIAL ACUTE-ON-CHRONIC LIVER FAILURE IN PATIENTS WITH CIRRHOSIS ADMITTED TO HOSPITAL WITH ACUTE DECOMPENSATION  Giacomo Zaccherini,

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Presentation on theme: "PREDICTION OF NOSOCOMIAL ACUTE-ON-CHRONIC LIVER FAILURE IN PATIENTS WITH CIRRHOSIS ADMITTED TO HOSPITAL WITH ACUTE DECOMPENSATION  Giacomo Zaccherini,"— Presentation transcript:

1 PREDICTION OF NOSOCOMIAL ACUTE-ON-CHRONIC LIVER FAILURE IN PATIENTS WITH CIRRHOSIS ADMITTED TO HOSPITAL WITH ACUTE DECOMPENSATION  Giacomo Zaccherini, Maurizio Baldassarre, Michele Bartoletti, Manuel Tufoni, Sonia Berardi, Mariarosa Tamè, Lucia Napoli, Antonio Siniscalchi, Angela Fabbri, Lorenzo Marconi, Agnese Antognoli, Giulia Iannone, Marco Domenicali, Pierluigi Viale, Franco Trevisani, Mauro Bernardi, Paolo Caraceni  JHEP Reports  DOI: /j.jhepr Copyright © Terms and Conditions

2 JHEP Reports DOI: (10.1016/j.jhepr.2019.07.005)
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3 Fig. 1 Patients with an acute decompensation of cirrhosis (AD) included in the analysis divided according to the presence of acute-on-chronic liver failure (ACLF) at study inclusion or the development of ACLF during hospital stay. JHEP Reports DOI: ( /j.jhepr ) Copyright © Terms and Conditions

4 Fig. 2 Estimated probability of developing ACLF during hospitalization (solid line) and 95% confidence intervals (dotted lines) according to hemoglobin level (A), leucocyte count (B), and MELD score (C) at hospital admission. JHEP Reports DOI: ( /j.jhepr ) Copyright © Terms and Conditions

5 Fig. 3 Cumulative incidence of Acute-on-Chronic Liver Failure (ACLF) during hospitalization in patients presenting none, 1, 2 or 3 risk factors at hospital admission, including hemoglobin level below 9.8g/dL, leucocyte count and MELD score above 5.59×109/L and 13 points respectively. JHEP Reports DOI: ( /j.jhepr ) Copyright © Terms and Conditions

6 Fig. 4 Probability of the development of Acute-on-Chronic Liver Failure (ACLF) during hospitalization in patients presenting none 1, 2 or 3 risk factors according to the development of nosocomial infection during hospitalization. JHEP Reports DOI: ( /j.jhepr ) Copyright © Terms and Conditions


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