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Diastolic dysfunction in sickle cell
by Gregory J. Kato, and Vandana Sachdev Blood Volume 116(1):1-2 July 8, 2010 ©2010 by American Society of Hematology
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Representative echocardiographic images from a patient with sickle cell disease.
Representative echocardiographic images from a patient with sickle cell disease. (A) Apical 4-chamber view showing concentric left ventricular hypertrophy and a dilated left atrium. (B) Doppler of the mitral inflow used to obtain a peak E velocity for early ventricular filling. (C) Tissue Doppler of the lateral mitral annulus used to obtain a peak e′ velocity. The E/e′ ratio is an indicator of left ventricular filling pressures and is used in the assessment of diastolic dysfunction. Gregory J. Kato, and Vandana Sachdev Blood 2010;116:1-2 ©2010 by American Society of Hematology
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