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Prevalence and risks of allosensitization in HeartMate left ventricular assist device recipients: The impact of leukofiltered cellular blood product transfusions 

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Presentation on theme: "Prevalence and risks of allosensitization in HeartMate left ventricular assist device recipients: The impact of leukofiltered cellular blood product transfusions "— Presentation transcript:

1 Prevalence and risks of allosensitization in HeartMate left ventricular assist device recipients: The impact of leukofiltered cellular blood product transfusions  Stavros G. Drakos, MD, James C. Stringham, MD, James W. Long, MD, PhD, Edward M. Gilbert, MD, Thomas C. Fuller, PhD, Beverly K. Campbell, RN, Benjamin D. Horne, PhD, MPH, Mary E. Hagan, FNP, Karl E. Nelson, RN, Judy M. Lindblom, MT, Patty A. Meldrum, RN, Joanne F. Carlson, MS, NP, Stephanie A. Moore, MD, Abdallah G. Kfoury, MD, Dale G. Renlund, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 133, Issue 6, Pages (June 2007) DOI: /j.jtcvs Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Time course of development of sensitization (panel reactive antibody [PRA] >10%) after left ventricular assist device (LVAD) implantation. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Kaplan–Meier analysis of incidence of sensitization among left ventricular assist device (LVAD) recipients who either did or did not receive cellular blood product transfusions. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Kaplan–Meier analysis of incidence of transplantation among left ventricular assist device (LVAD) recipients who either did or did not receive cellular blood product transfusions. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 Kaplan–Meier analysis of rates of transplantation in left ventricular assist device recipients who either did (panel reactive antibody > 10%) or did not acquire allosensitization. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions


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