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Kaplan-Meier analysis of mice treated with rifampin (dashed line) and ceftriaxone (solid line) for experimental S. pneumoniae meningitis. Kaplan-Meier.

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Presentation on theme: "Kaplan-Meier analysis of mice treated with rifampin (dashed line) and ceftriaxone (solid line) for experimental S. pneumoniae meningitis. Kaplan-Meier."— Presentation transcript:

1 Kaplan-Meier analysis of mice treated with rifampin (dashed line) and ceftriaxone (solid line) for experimental S. pneumoniae meningitis. Kaplan-Meier analysis of mice treated with rifampin (dashed line) and ceftriaxone (solid line) for experimental S. pneumoniae meningitis. Reprinted from reference 122 with permission of the publisher. Note the high early mortality in animals treated with ceftriaxone. The survival-versus-time curves for the two antibiotics were significantly different (P = 0.007; Cox proportional hazard model). Rifampin reduced overall mortality from 49 to 26% (P = 0.04, Fisher’s exact test). Roland Nau, and Helmut Eiffert Clin. Microbiol. Rev. 2002; doi: /CMR

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