1. PPAR-gamma receptor ligand induces regression of endometrial explants in baboons: A prospective, randomized, placebo- and drug-controlled study 
Dan I. Lebovic, M.D., M.A., Jason M. Mwenda, Ph.D., Daniel C. Chai, D.V.M., Michael D. Mueller, M.D., Allessandro Santi, M.D., Senait Fisseha, M.D., J.D., Thomas D'Hooghe, M.D., Ph.D. 
Fertility and Sterility 
Volume 88, Issue 4, Pages (October 2007)
DOI: /j.fertnstert
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Laparoscopic gross appearance of endometriotic lesions in three representative baboons at staging laparoscopy (left panels) and 30 days after treatment (right panels). The staging endometriotic lesions (arrows) range from white-orange plaques, red vesicles, and typical blue-black to red polypoid excrescences. The final laparoscopy after treatment reveals black plaques, clear vesicles, and white fibrotic nodules (arrowheads). (A) Baboon PAN 2985 before and after placebo treatment. (B) Baboon PAN 2871 before and after ganirelix treatment. (C) Baboon PAN 3030 before and after rosiglitazone.
Lebovic. Rosiglitazone inhibits endometriosis in baboons. Fertil Steril 2007.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

3. Figure 2
Surface area box plot showing changes in total surface area (mm2) before and after treatments with, placebo, GnRH-antagonist, and rosiglitazone (four baboons/group). Horizontal small bars represent the 10th to 90th percentile range, and the boxes indicate the 25th to 75th percentile range. The horizontal line in each box corresponds to the median. (∗ indicates univariate ANOVA: post-hoc Dunnett t-test P=.028, Tukey P=.037, Bonferroni P=0.046; NS = nonsignificant).
Lebovic. Rosiglitazone inhibits endometriosis in baboons. Fertil Steril 2007.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

4. Figure 3
Box plot showing relative change in surface area (surface area after treatment minus surface area before divided by surface area before) for the three treatment groups (four baboons/group): placebo, GnRH-antagonist, rosiglitazone. (∗ indicates univariate ANOVA: post-hoc Dunnett t-test P<.05; † indicates post hoc Dunnett t-test P=.024, Tukey P=.033, Bonferroni P=.04).
Lebovic. Rosiglitazone inhibits endometriosis in baboons. Fertil Steril 2007.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

5. Figure 4
Stack bar of mean number of lesions by lesion type. Quantitative distribution of lesion types before (A) and after (B) treatment for 30 days with placebo, GnRH-antagonist, and rosiglitazone.
Lebovic. Rosiglitazone inhibits endometriosis in baboons. Fertil Steril 2007.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

6. Figure 5
Stack bar of mean surface area of lesions by lesion type. Distribution of the mean surface area by lesion types before (A) and after (B) treatment for 30 days with, placebo, GnRH-antagonist, and rosiglitazone.
Lebovic. Rosiglitazone inhibits endometriosis in baboons. Fertil Steril 2007.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

7. Figure 6
Serum hormone levels before and after drug treatment. Box plot graphic of serum E2 and P concentrations in the three treatment groups (four baboons/group) consisting of placebo, GnRH-antagonist, and rosiglitazone at laparoscopy 2 (LS2) and at laparoscopy 3, 30 days after respective treatments (LS3). There was no significant difference in E2 or P concentration within groups before and after treatment or between groups at time of staging laparoscopy or at end of treatment laparoscopy (univariate ANOVA, P>.3). Horizontal small bars represent the 10th to 90th percentile range, and the boxes indicate the 25th to 75th percentile range. The horizontal line in each box corresponds to the median.
Lebovic. Rosiglitazone inhibits endometriosis in baboons. Fertil Steril 2007.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions